医学
心脏病学
内科学
房性心动过速
良性循环与恶性循环
心动过速
心肌病
心力衰竭
导管消融
心房颤动
经济
宏观经济学
标识
DOI:10.1111/j.1540-8167.1998.tb00114.x
摘要
AF‐Induced Electrophysiologic Remodeling. Introduction : With few exceptions, acquired heart di.sease is the result of (gradual changes in the heart, progressing during several months or years. This also includes certain cardiac arrhythmias, as for instance atrial fihrillation (AF). In spite of the important role of slowly progressing pathologic processes, most of our knowledge about mechanisms of cardiac arrhythmias is hased on acute experiments. Only recently, the attention also is more focused on long‐term adaptation processes like cardiac memory, electrical remodeling, and tachycardia‐induced cardiomyopathy. In experimental animal models, it has heen shown that AF induces a vicious circle of electrophysiologic and structural changes that inevitahly leads to “domestication” of the arrhythmia (“AF begets AF”). In this article, the studies on AF‐induced electrophysiologic and cellular remodeling are discussed.
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