医学
核医学
放射科
血管造影
灌注扫描
冲程(发动机)
灌注
计算机断层血管造影
头颈部
急性中风
外科
内科学
机械工程
工程类
组织纤溶酶原激活剂
作者
Xiaping Mo,Yu Cui,Jing Yuan,Zufei Hang,Xueyuan Jiang,Gaoxiong Duan,Lan Liang,Zengchao Huang,Shasha Li,Peiyi Sun,Wei Chen,Lanzhen Wei,Ying Guo,Demao Deng
标识
DOI:10.1016/j.ejrad.2022.110426
摘要
Purpose We sought to evaluate the performance of a new “one-stop-shop” scan protocol combining brain computed tomography perfusion (CTP) and head-and-neck CT angiography (CTA) imaging for acute stroke patients using a 256-detector CT scanner. Method From March to August 2020, 60 patients (30 men and 30 women) aged 22–88 years with suspected acute stroke were enrolled and randomly divided into 2 groups to undergo brain CTP and head-and-neck CTA with a 256-detector CT system. Group A used traditional scan protocol with a separate brain CTP and head-and-neck CT examination that included non–contrast-enhanced and contrast-enhanced acquisitions; group B used the new “one-stop-shop” scan protocol with head-and-neck CTA data inserted into brain CTP scans at the peak time (PT) of the arterial phase. The insertion point of the head-and-neck CTA data was determined by a test bolus. The examination time, contrast dose, radiation dose, and image quality were compared between the groups. Results The total contrast dose was reduced by 40% in group B compared to group A (60 mL vs. 100 mL). The imaging time was 52.5 ± 2.6 s in group B and 74.9 ± 3.3 s in group A, showing a reduction of approximately 43% in group B. There was no significant difference in image quality both quantitatively and qualitatively between the groups (all P > 0.05). Group B had a slight reduction in dose length product (1139.0 ± 45.3 vs. 1211.6 ± 31.9 mGy·cm, P < 0.001). Conclusions The proposed “one-stop-shop” scan protocol combining brain CTP and head-and-neck CTA on a 256-detector CT system can reduce imaging time and contrast dose, without affecting image quality or perfusion results, compared to the traditional protocol of separating the examinations.
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