Basal Cell Adenoma and Basal Cell Adenocarcinoma

Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are uncommon biphasic salivary gland tumors having morphologic similarities to other biphasic salivary gland neoplasms having differentiation toward the intercalated ducts of the salivary gland. Both tumors show mixtures of trabecular, tubular, solid, and membranous solid patterns. BCAC is separated from BCA primarily by the presence of invasion in the former. The diagnosis of BCA and BCAC is best carried out with hematoxylin and eosin-stained sections and careful attention to detail of tumors in the differential diagnosis, including adenoid cystic carcinoma, pleomorphic adenoma, and epithelial myoepithelial carcinoma.