Serial Histological Sectioning of the Intact Mouse Hind Paw for Quantification of the Anatomical Distribution of Meissner-like Corpuscles across the Skin

Introduction The skin forms a barrier with the surrounding environment, protecting the body from chemical, mechanical and thermal exposure and enabling the sensation of heat, cold, pain and touch [1-3]. Mammalian glabrous skin is specialized for discriminative touch and mobility, enabling controlled movements during gait and balance [2,4]. Critical to this