心理学
精神病理学
分裂情感障碍
生活质量(医疗保健)
精神分裂症(面向对象编程)
临床心理学
性唤起
高潮
精神科
阳性与阴性症状量表
性欲
性功能障碍
精神病
人类性学
性行为
心理治疗师
社会学
性别研究
作者
Xiaoduo Fan,David C. Henderson,Elaine Y. Chiang,Leah B. Namey Briggs,Oliver Freudenreich,A. Eden Evins,Corinne Cather,Donald Goff
标识
DOI:10.1016/j.schres.2007.04.033
摘要
The present study was to characterize relationships among sexual functioning, schizophrenia symptoms and quality of life measures. In addition, sexual functioning was compared among patients treated with different antipsychotic agents.Outpatient subjects were assessed using the Positive and Negative Symptom Scale (PANSS), the Changes in Sexual Functioning Questionnaire (CSFQ) and the Hamilton Rating Scale for Depression (HAMD). Quality of life was assessed using two different instruments: observer-rated Heinrich's Quality of Life Scale (QLS) and self-rated The Behavior and Symptom Identification Scale (BASIS).One hundred twenty-four patients with schizophrenia or schizoaffective disorder were enrolled in the study. Eight-six patients (69%) completed at least part of the CSFQ assessment, which generated at least one valid subscale score. High rates of sexual impairment were found in both male and female patients (65%-94% across different subscales). For males, higher scores on the PANSS-positive subscale were associated with a lower frequency of sexual activity (p=0.04). For females, higher scores on the PANSS-positive subscale and PANSS-general psychopathology subscale were significantly associated with more difficulty in both sexual arousal and orgasm (p's<0.05). For both males and females, there were no significant relationships between any CSFQ subscale measures and the quality of life measures (p's>0.05). No significant differences were found among three antipsychotic treatment groups (clozapine, olanzapine or typical agents) on any CSFQ subscale measures or quality of life measures after controlling for PANSS total scores (p's>0.05).Effective treatment strategies still need to be developed to address sexual dysfunction and quality of life in patients with schizophrenia.
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