氢化酶
火球菌属
生物化学
化学
葡萄糖酸
制氢
酶
催化作用
古细菌
基因
作者
Jonathan Woodward,Susan M. Mattingly,Michael J. Danson,David W. Hough,Nicholas Ward,Michael W. W. Adams
摘要
A new in vitro enzymatic pathway for the generation of molecular hydrogen from glucose has been demonstrated. The reaction is based on the oxidation of glucose by Thermoplasma acidophilum glucose dehydrogenase with the concomitant oxidation of NADPH by Pyrococcus furiosus hydrogenase. Stoichiometric yields of hydrogen were produced from glucose with the continuous recycling of cofactor. This simple system may provide a method for the biological production of hydrogen from renewable sources. In addition, the other product of this reaction, gluconic acid, is a high-value chemical commodity.
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