PFG NMR diffusion experiments for complex systems

Concepts in Magnetic Resonance Part AVolume 28A, Issue 4 p. 249-269 Free to Read PFG NMR diffusion experiments for complex systems Konstantin I. Momot, Corresponding Author Konstantin I. Momot [email protected] School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, AustraliaSchool of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, AustraliaSearch for more papers by this authorPhilip W. Kuchel, Philip W. Kuchel School of Molecular and Microbial Biosciences, University of Sydney, Sydney, New South Wales 2006, AustraliaSearch for more papers by this author Konstantin I. Momot, Corresponding Author Konstantin I. Momot [email protected] School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, AustraliaSchool of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, AustraliaSearch for more papers by this authorPhilip W. Kuchel, Philip W. Kuchel School of Molecular and Microbial Biosciences, University of Sydney, Sydney, New South Wales 2006, AustraliaSearch for more papers by this author First published: 14 July 2006 https://doi.org/10.1002/cmr.a.20056Citations: 58AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Many practical applications of diffusion NMR, ranging from biomedical to industrial, entail the measurement of low-concentration solutes in nondeuterated, compositionally complex systems. This article presents examples of robust, versatile diffusion experiments that can be used with nondeuterated solvents at nonambient temperatures. Specifically, three experiments are presented in detail: CONVEX, which combines excitation-sculpting solvent suppression with double-echo convection-compensating PGSE; DQDiff, which implements double-quantum filtered diffusion measurements in a convection-compensating mode; and applications of oscillating-gradient spin-echo (OGSE) to systems with homonuclear scalar couplings. These examples are based on the recent work by the authors and relate to a variety of systems, ranging from simple solutions to colloidal and polymeric systems. Besides the applied aspects, we review the general methodology used to treat the effects of diffusion and flow in NMR experiments, and apply this theory to derive the diffusion attenuation expression for each of the experiments presented. 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