再现性
协调
一致性
扫描仪
医学物理学
重采样
计算机科学
医学
成像体模
核医学
生物医学工程
人工智能
数学
统计
内科学
物理
声学
作者
Abdalla Ibrahim,Turkey Refaee,Sergey Primakov,Bruno Barufaldi,Raymond J. Acciavatti,Renée W. Y. Granzier,Roland Hustinx,Felix M. Mottaghy,Henry C. Woodruff,Joachim E. Wildberger,Philippe Lambin,Andrew D. A. Maidment
出处
期刊:Cancers
[Multidisciplinary Digital Publishing Institute]
日期:2021-04-13
卷期号:13 (8): 1848-1848
被引量:44
标识
DOI:10.3390/cancers13081848
摘要
While handcrafted radiomic features (HRFs) have shown promise in the field of personalized medicine, many hurdles hinder its incorporation into clinical practice, including but not limited to their sensitivity to differences in acquisition and reconstruction parameters. In this study, we evaluated the effects of differences in in-plane spatial resolution (IPR) on HRFs, using a phantom dataset (n = 14) acquired on two scanner models. Furthermore, we assessed the effects of interpolation methods (IMs), the choice of a new unified in-plane resolution (NUIR), and ComBat harmonization on the reproducibility of HRFs. The reproducibility of HRFs was significantly affected by variations in IPR, with pairwise concordant HRFs, as measured by the concordance correlation coefficient (CCC), ranging from 42% to 95%. The number of concordant HRFs (CCC > 0.9) after resampling varied depending on (i) the scanner model, (ii) the IM, and (iii) the NUIR. The number of concordant HRFs after ComBat harmonization depended on the variations between the batches harmonized. The majority of IMs resulted in a higher number of concordant HRFs compared to ComBat harmonization, and the combination of IMs and ComBat harmonization did not yield a significant benefit. Our developed framework can be used to assess the reproducibility and harmonizability of RFs.
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