生物相容性
模拟体液
超亲水性
钛
生物矿化
腐蚀
材料科学
化学工程
表面改性
各向同性腐蚀
纳米技术
骨整合
润湿
图层(电子)
蚀刻(微加工)
复合材料
冶金
植入
扫描电子显微镜
医学
外科
工程类
标识
DOI:10.1016/0038-1098(72)91022-8
摘要
Surface structures of medical implants generally play a crucial role in tissue growth and healing while implanted into a living body. The surface design and modification of implants can effectively promote its biocompatibility and integration ability. In this study, a hierarchically superhydrophilic structure on titanium surface with a nano-spongelike titania layer on the micro-roughened titanium surface was constructed through dual acid etching and electrochemical treatments. It is shown that the structure of micro/nano-spongelike TiO2 provides not only better corrosion resistance and less oxygen vacancies, but also much higher ability of biomineralization after immersion in simulated body fluid (SBF) for 14 days. It is evident, by the cell culture for the different samples, that the micro–nano spongelike structured surface on Ti significantly promotes human osteoblast-like MG63 cell attachment and proliferation. All evaluations of electrochemical behavior and biological responses in this study indicate that the micro/nano-spongelike structure on Ti surface is of excellent chemical stability, bioactivity as well as biocompatibility for biomedical implant applications.
科研通智能强力驱动
Strongly Powered by AbleSci AI