The In-Vitro Activity of a Cold Atmospheric Plasma Device Utilizing Ambient Air against Bacteria and Biofilms Associated with Periodontal or Peri-Implant Diseases

核梭杆菌 生物膜 牙龈卟啉单胞菌 连翘 格氏链球菌 连翘 微生物学 变形链球菌 化学 中间普氏菌 口腔链球菌 牙本质 聚集放线菌 种植周围炎 细菌 牙周炎 菌落形成单位 牙科 梭杆菌 植入 医学 生物 病理 外科 拟杆菌 金银花 替代医学 中医药 遗传学
作者
Gert Jungbauer,Leandro Favaro,Steffen Müller,Anton Sculean,Sigrun Eick
出处
期刊:Antibiotics [Multidisciplinary Digital Publishing Institute]
卷期号:11 (6): 752-752 被引量:20
标识
DOI:10.3390/antibiotics11060752
摘要

Due to its antimicrobial and healing-promoting effects, the application of cold atmospheric plasma (CAP) appears to be a promising modality in various fields of general medicine and dentistry. The aim of the present study was to evaluate the antibacterial and anti-biofilm activity of a handheld device utilizing ambient air for plasma generation. Suspensions of 11 oral bacteria (among them Fusobacterium nucleatum, Porphyromonas gingivalis, Parvimonas micra, Streptococcus gordonii, and Tannerella forsythia) were exposed to CAP for 10, 30, 60, and 120 s. Before and after treatment, colony forming unit (CFU) counts were determined. Then, 12-species biofilms were cultured on dentin and titanium specimens, and CAP was applied for 30, 60, and 120 s before quantifying CFU counts, biofilm mass, and metabolic activity. A reduction of ≥3 log10 CFU, was found for ten out of the eleven tested species at 30 s (except for T. forsythia) and for all species at 60 s. For biofilm grown on dentin and titanium specimens, the log10 reductions were 2.43 log10 CFU/specimen and by about 4 log10 CFU/specimen after 120 s of CAP. The CAP application did not reduce the biomass significantly, the metabolic activity of the biofilms on dentin and titanium decreased by 98% and 95% after 120 s of CAP. An application of 120 s of CAP had no cytotoxic effect on gingival fibroblasts and significantly increased the adhesion of gingival fibroblasts to the titanium surface. These results are promising and underline the potential of CAP for implementation in periodontal and peri-implantitis therapy.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
2秒前
脑洞疼应助科研通管家采纳,获得10
4秒前
汉堡包应助科研通管家采纳,获得10
4秒前
共享精神应助科研通管家采纳,获得10
4秒前
今后应助科研通管家采纳,获得10
4秒前
科研通AI2S应助科研通管家采纳,获得10
5秒前
细腻万声完成签到,获得积分10
5秒前
5秒前
5秒前
王李俊完成签到,获得积分10
5秒前
7秒前
Jasper应助ybki采纳,获得10
10秒前
Lucas应助如意的代萱采纳,获得10
10秒前
科研通AI6.2应助xiaxia采纳,获得10
11秒前
在水一方应助Sea_U采纳,获得10
13秒前
共享精神应助杨武天一采纳,获得10
13秒前
科研通AI6.4应助杨武天一采纳,获得10
13秒前
炽魂妖应助杨武天一采纳,获得30
13秒前
科研通AI6.3应助杨武天一采纳,获得10
13秒前
华仔应助杨武天一采纳,获得10
13秒前
科研通AI6.2应助杨武天一采纳,获得10
13秒前
田様应助杨武天一采纳,获得10
13秒前
丘比特应助杨武天一采纳,获得10
13秒前
科目三应助杨武天一采纳,获得10
13秒前
脑洞疼应助杨武天一采纳,获得10
13秒前
萝卜花发布了新的文献求助10
14秒前
落雨冥完成签到,获得积分10
14秒前
莫妮卡完成签到,获得积分10
15秒前
15秒前
星辰大海应助细腻万声采纳,获得10
16秒前
毛毛完成签到,获得积分10
16秒前
18秒前
充电宝应助大柒采纳,获得10
19秒前
乐乐发布了新的文献求助10
21秒前
旺仔不甜完成签到,获得积分10
21秒前
Mryuan完成签到,获得积分10
22秒前
23秒前
23秒前
23秒前
高分求助中
Malcolm Fraser : a biography 700
Signals, Systems, and Signal Processing 610
天津市智库成果选编 600
Climate change and sports: Statistics report on climate change and sports 500
Forced degradation and stability indicating LC method for Letrozole: A stress testing guide 500
Organic Reactions Volume 118 400
A Foreign Missionary on the Long March: The Unpublished Memoirs of Arnolis Hayman of the China Inland Mission 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 纳米技术 工程类 有机化学 化学工程 生物化学 计算机科学 物理 内科学 复合材料 催化作用 物理化学 光电子学 电极 细胞生物学 基因 无机化学
热门帖子
关注 科研通微信公众号,转发送积分 6461853
求助须知:如何正确求助?哪些是违规求助? 8270076
关于积分的说明 17629803
捐赠科研通 5532820
什么是DOI,文献DOI怎么找? 2906625
邀请新用户注册赠送积分活动 1883406
关于科研通互助平台的介绍 1729581