医学
乙胺丁醇
吡嗪酰胺
乙氧酰胺
异烟肼
左氧氟沙星
卷曲霉素
肺结核
莫西沙星
利福平
怀孕
环丝氨酸
妊娠期
外科
内科学
作者
Klaus-Dieter K.L. Lessnau,Samer Qarah
出处
期刊:Chest
[Elsevier]
日期:2003-03-01
卷期号:123 (3): 953-956
被引量:34
标识
DOI:10.1378/chest.123.3.953
摘要
A woman at 23 weeks' gestation was treated with rifampin, isoniazid, and ethambutol for cavitary tuberculosis (TB). She did not respond within 3 weeks, and multidrug-resistant (MDR) TB was suspected. Direct plating on susceptibility media was performed immediately. Treatment was initiated with IV capreomycin, levofloxacin, para-aminosalicylic acid, pyrazinamide, cycloserine, and high-dose vitamin B 6 at 26 weeks' gestation. The patient delivered vaginally at week 35. The newborn was not infected. Following delivery, ethionamide was added as a sixth drug, and levofloxacin was replaced with moxifloxacin. The patient's sputum became smear-negative and culture-negative for TB. All reported cases of MDR-TB during pregnancy are reviewed.
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