23S核糖体RNA
脓肿分枝杆菌
克拉霉素
聚合酶链反应
微生物学
生物
分枝杆菌
亚种
基因
遗传学
抗生素
细菌
核糖核酸
核糖体
古生物学
作者
H Y Kim,S Y Lee,B J Kim,Yoon Hoh Kook
标识
DOI:10.4103/0255-0857.188355
摘要
On the basis of the structural differences of erm, we used a duplex polymerase chain reaction (PCR) to differentiate Mycobacterium abscessus subsp. abscessus and subsp. massiliense isolates and to detect the point mutations of 23S rRNA gene that confer a high level of resistance to clarithromycin. Subsp. massiliense strains occupying almost half of the clinical isolates can be simply identified, and their clarithromycin susceptibility can be rapidly determined.
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