结直肠癌
盐霉素
癌症研究
连环素
医学
癌症
生物
Wnt信号通路
肿瘤科
生物信息学
内科学
信号转导
细胞生物学
遗传学
抗生素
作者
Zhongyuan Wang,Liang Zhou,Yanpeng Xiong,Shubin Yu,Huan Li,Jiaoyang Fan,Fan Li,Zijie Su,Jiaxing Song,Qi Sun,Shanshan Liu,Yuqing Xia,Liang Zhao,Shiyue Li,Fang Guo,Peng Huang,Dennis A. Carson,Desheng Lu
摘要
Salinomycin is a well-known inhibitor of human cancer stem cells (CSCs). However, the molecular mechanism(s) by which salinomycin targets colorectal CSCs is poorly understood. Here, we have investigated underlying antitumour mechanisms of salinomycin in colorectal cancer cells and three tumour models.
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