衰老
特发性肺纤维化
肺纤维化
医学
纤维化
肺
病理
癌症研究
免疫学
内科学
作者
Changfu Yao,Xiangrong Guan,Gianni Carraro,Tanyalak Parimon,Xue Liu,Guanling Huang,Apoorva Mulay,Harmik J. Soukiasian,Gregory David,S. Weigt,John A. Belperio,Peter Chen,Dianhua Jiang,Paul W. Noble,Barry R. Stripp
标识
DOI:10.1164/rccm.202004-1274oc
摘要
Senescence of AT2 cells is sufficient to drive progressive pulmonary fibrosis. Early attenuation of senescence-related pathways and elimination of senescent cells are promising therapeutic approaches to prevent pulmonary fibrosis.
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