白色念珠菌
化学
树突状细胞
细胞生物学
白色体
骨髓
癌症研究
兰格林
生物
滤泡树突状细胞
免疫系统
细胞毒性T细胞
T细胞
作者
Joanne Gibson,Neil A. R. Gow,Simon Y. C. Wong
出处
期刊:Methods of Molecular Biology
日期:2012-01-01
卷期号:845: 261-275
标识
DOI:10.1007/978-1-61779-539-8_17
摘要
Dendritic cells (DCs) detect and respond to microbes or their components by producing cytokines and other molecules that can activate the proliferation and differentiation pathways of T cells. Investigation of DC responses to pathogens would thus provide important insights into how T-cell responses most appropriate for the pathogen are induced. Here, we describe methods for the use of mixed leukocyte reactions, to determine the proliferative and cytokine responses of murine splenic T cells in response to co-culture with bone marrow-derived DCs stimulated with Candida albicans.
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