V_2O_5/TiO_2 selective catalytic reduction (SCR) catalyst for DeNOx application was prepared using nanoparticle TiO_2 as the carrier and V_2O_5 as the active component.Preparation and catalytic properties of the catalyst for NOx removal were studied and phase change and sintering temperature of the catalyst were characterized by DSC.The results showed that V_2O_5 enhanced the catalytic activity for SCR reaction,with NO conversion of 97.5% attainable over 6% V_2O_5-94% TiO_2 in temperature range of (300-420) ℃.