化学
恶唑啉
硼氢化
对映选择合成
芳基
催化作用
配体(生物化学)
组合化学
有机化学
受体
生物化学
烷基
作者
Jianhui Chen,Tuo Xi,Zhan Lu
出处
期刊:Organic Letters
[American Chemical Society]
日期:2014-12-01
卷期号:16 (24): 6452-6455
被引量:135
摘要
The highly regio- and enantioselective iron-catalyzed anti-Markovnikov hydroboration of 1,1-disubstituted aryl alkenes is reported by using a novel chiral iminopyridine oxazoline (IPO) ligand, in which the iminopyridine group is proposed to stabilize the iron and chiral oxazoline group to control enantioselectivity. This distinct class of reactive IPO ligands will likely be of high value for a large variety of asymmetric transformations using first-row transition metals.
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