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Journal of Clinical PeriodontologyVolume 51, Issue 3 p. 365-365 LETTER TO THE EDITOR MMP-8 and active MMP-8 (aMMP-8) are not synonymous in periodontal disease diagnostics Vaibhav Sahni, Vaibhav Sahni Private Practice, New Delhi, IndiaSearch for more papers by this authorIsmo Tapani Räisänen, Corresponding Author Ismo Tapani Räisänen [email protected] orcid.org/0000-0001-5821-5299 Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland Correspondence Ismo Tapani Räisänen, Department of Oral and Maxillofacial Diseases, Head and Neck Center, University of Helsinki and Helsinki University Hospital, PO Box 63 (Haartmaninkatu 8) FI-00014, Helsinki, Finland. Email: [email protected]Search for more papers by this authorTimo Sorsa, Timo Sorsa Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland Department of Oral Diseases, Karolinska Institutet, Stockholm, SwedenSearch for more papers by this author Vaibhav Sahni, Vaibhav Sahni Private Practice, New Delhi, IndiaSearch for more papers by this authorIsmo Tapani Räisänen, Corresponding Author Ismo Tapani Räisänen [email protected] orcid.org/0000-0001-5821-5299 Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland Correspondence Ismo Tapani Räisänen, Department of Oral and Maxillofacial Diseases, Head and Neck Center, University of Helsinki and Helsinki University Hospital, PO Box 63 (Haartmaninkatu 8) FI-00014, Helsinki, Finland. Email: [email protected]Search for more papers by this authorTimo Sorsa, Timo Sorsa Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland Department of Oral Diseases, Karolinska Institutet, Stockholm, SwedenSearch for more papers by this author First published: 10 January 2024 https://doi.org/10.1111/jcpe.13923Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Open Research DATA AVAILABILITY STATEMENT Data sharing is not applicable to this article as no new data were created or analyzed in this study. REFERENCES Baeza, M., Garrido, M., Hernández-Ríos, P., Dezerega, A., García-Sesnich, J., Strauss, F., Aitken, J. P., Lesaffre, E., Vanbelle, S., Gamonal, J., Brignardello-Petersen, R., Tervahartiala, T., Sorsa, T., & Hernández, M. (2016). Diagnostic accuracy for apical and chronic periodontitis biomarkers in gingival crevicular fluid: An exploratory study. Journal of Clinical Periodontology, 43(1), 34–45. 10.1111/jcpe.12479 CASPubMedWeb of Science®Google Scholar Blanco-Pintos, T., Regueira-Iglesias, A., Seijo-Porto, I., Balsa-Castro, C., Castelo-Baz, P., Nibali, L., & Tomás, I. (2023). Accuracy of periodontitis diagnosis obtained using multiple molecular biomarkers in oral fluids: A systematic review and meta-analysis. Journal of Clinical Periodontology, 50, 1420–1443. https://doi.org/10.1111/jcpe.13854 10.1111/jcpe.13854 CASPubMedWeb of Science®Google Scholar Lee, W., Aitken, S., Sodek, J., & McCulloch, C. A. (1995). Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: Role of active enzyme in human periodontitis. Journal of Periodontal Research, 30(1), 23–33. https://doi.org/10.1111/j.1600-0765.1995.tb01249.x 10.1111/j.1600-0765.1995.tb01249.x CASPubMedWeb of Science®Google Scholar Sorsa, T., Nwhator, S. O., Sakellari, D., Grigoriadis, A., Umeizudike, K. A., Brandt, E., Keskin, M., Tervahartiala, T., Pärnänen, P., Gupta, S., Mohindra, R., Bostanci, N., Buduneli, N., & Räisänen, I. T. (2022). aMMP-8 oral fluid PoC test in relation to oral and systemic diseases. Frontiers in Oral Health, 3, 897115. 10.3389/froh.2022.897115 PubMedGoogle Scholar Umeizudike, K., Räisänen, I., Gupta, S., Nwhator, S., Grigoriadis, A., Sakellari, D., & Sorsa, T. (2022). Active matrix metalloproteinase-8: A potential biomarker of oral systemic link. Cllinical and Experimental Dental Research, 8(1), 359–365. https://doi.org/10.1002/cre2.516 10.1002/cre2.516 PubMedWeb of Science®Google Scholar Volume51, Issue3March 2024Pages 365-365 ReferencesRelatedInformation