医学
大流行
心肌炎
心肌梗塞
疾病
急性冠脉综合征
冠状动脉疾病
心力衰竭
重症监护医学
冠状病毒
2019年冠状病毒病(COVID-19)
内科学
心脏病学
传染病(医学专业)
作者
Peter K. Boulos,Scott Freeman,Timothy D. Henry,Ehtisham Mahmud,John C. Messenger
出处
期刊:Circulation Research
[Ovid Technologies (Wolters Kluwer)]
日期:2023-05-12
卷期号:132 (10): 1259-1271
被引量:2
标识
DOI:10.1161/circresaha.122.321952
摘要
The onset and widespread dissemination of the severe acute respiratory syndrome coronavirus-2 in late 2019 impacted the world in a way not seen since the 1918 H1N1 pandemic, colloquially known as the Spanish Flu. Much like the Spanish Flu, which was observed to disproportionately impact young adults, it became clear in the early days of the coronavirus disease 2019 (COVID-19) pandemic that certain groups appeared to be at higher risk for severe illness once infected. One such group that immediately came to the forefront and garnered international attention was patients with preexisting cardiovascular disease. Here, we examine the available literature describing the interaction of COVID-19 with a myriad of cardiovascular conditions and diseases, paying particular attention to patients diagnosed with arrythmias, heart failure, and coronary artery disease. We further discuss the association of acute COVID-19 with de novo cardiovascular disease, including myocardial infarction due to coronary thrombosis, myocarditis, and new onset arrhythmias. We will evaluate various biochemical theories to explain these findings, including possible mechanisms of direct myocardial injury caused by the severe acute respiratory syndrome coronavirus-2 virus at the cellular level. Finally, we will discuss the strategies employed by numerous groups and governing bodies within the cardiovascular disease community to address the unprecedented challenges posed to the care of our most vulnerable patients, including heart transplant recipients, end-stage heart failure patients, and patients suffering from acute coronary syndromes, during the early days and height of the COVID-19 pandemic.
科研通智能强力驱动
Strongly Powered by AbleSci AI