Functional analysis of a down‐regulated transcription factor‐SoxNeuroA gene involved in the acaricidal mechanism of scopoletin against spider mites

These results demonstrate that the acaricidal mechanism of scopoletin involves inhibition of the transcription factor SoxNeuroA, thus inducing the activation of the Orai1 Ca²⁺ channel, eventually leading to Ca²⁺ overload and lethality. Elucidation of the transcription factor-targeted mechanism for this potent plant-derived acaricide has vital implications for the design of next-generation green acaricides with novel targets. © 2023 Society of Chemical Industry.