医学
叙述性评论
伤口愈合
单线态氧
随机对照试验
重症监护医学
人体研究
系统回顾
梅德林
皮肤病科
外科
氧气
内科学
化学
有机化学
政治学
法学
作者
Martina Sýkorová,Christine Moffatt,Neil Stentiford,Ewa Anna Burian,Sasagaki Katsuhiro,Yang Wei
出处
期刊:PubMed
日期:2024-04-01
卷期号:21 (4): e14846-e14846
摘要
The aim of this scoping review was to provide an overview of current research into topical oxygen therapies including the under-researched singlet oxygen for wound healing. A scoping review was undertaken using five databases. After duplicates and ineligible studies were excluded, 49 studies were included for a narrative review. Out of the included 49 studies, 45 (91.8%) were published in the past 10 years (2013-2023) with 32 (65.3%) published in the past 5 years (2018-2023). Eight of the studies were systematic reviews and/or meta-analysis and 18 were RCTs. The search identified zero human RCTs on singlet oxygen, but one human cohort study and five studies in animals. There is evidence that topical oxygen therapy may be useful for the treatment of chronic wounds, mainly diabetic foot ulcers. Singlet oxygen has shown potential, but would need further confirmation in controlled human trials, including more research to understand the bio-properties.
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