基因组
原水
流动遗传元素
生物
抗生素耐药性
抗性(生态学)
不动杆菌
抵抗性
数据库
环境科学
生态学
抗生素
基因
基因组
微生物学
环境工程
遗传学
计算机科学
作者
Wei Wang,Wenhan Nie,Qing Gu,Wenjie Xie,Dinghui Yang,Hongyu Li,Peihong Wang,Weixue Liao,Jin Huang,Bi-Feng Yuan,Shengli Zhou,Iftikhar Ahmad,Kiga Kotaro,Gongyou Chen,Bo Zhu
标识
DOI:10.1016/j.watres.2024.121572
摘要
The exploration of antibiotic resistance genes (ARGs) in drinking water reservoirs is an emerging field. Using a curated database, we enhanced the ARG detection and conducted a comprehensive analysis using 2.2 Tb of deep metagenomic sequencing data to determine the distribution of ARGs across 16 drinking water reservoirs and associated environments. Our findings reveal a greater diversity of ARGs in sediments than in water, underscoring the importance of extensive background surveys. Crucial ARG carriers—specifically Acinetobacter, Pseudomonas, and Mycobacterium were identified in drinking water reservoirs. Extensive analysis of the data uncovered a considerable concern for drinking water safety, particularly in regions reliant on river sources. Mobile genetic elements have been found to contribute markedly to the propagation of ARGs. The results of this research suggest that the establishment of drinking water reservoirs for supplying raw water may be an effective strategy for alleviating the spread of water-mediated ARGs.
科研通智能强力驱动
Strongly Powered by AbleSci AI