免疫组织化学
阴道
人乳头瘤病毒
病理
乳头状瘤
缪勒模仿
病毒
混合瘤
医学
生物
癌症
解剖
内科学
病毒学
宫颈癌
作者
Matjaž Šebenik,Zhijije Yan,Walid E. Khalbuss,Khush Mittal
出处
期刊:Human Pathology
[Elsevier]
日期:2007-08-01
卷期号:38 (8): 1282-1288
被引量:21
标识
DOI:10.1016/j.humpath.2007.03.008
摘要
The patient was a 57-year-old white woman who presented with a 3.0 × 2.0-cm partially ulcerated vaginal polyp. Histology revealed a malignant mixed mullerian tumor composed of invasive squamous cell carcinoma with deeper areas of undifferentiated pleomorphic sarcoma. Invasive carcinoma had overlying high-grade vaginal intraepithelial neoplasia (VaIN III), which contained koilocytic atypia. In situ hybridization detected high-risk human papillomavirus DNA in both the carcinoma and the sarcoma components.
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