平滑
PI3K/AKT/mTOR通路
刺猬信号通路
癌症研究
髓母细胞瘤
生物
信号转导
刺猬
细胞生物学
药理学
作者
Silvia Buonamici,Juliet Williams,Michael Morrissey,Anlai Wang,Ribo Guo,Anthony Vattay,Kathy Hsiao,Jing Yuan,John Green,Beatriz Muñoz,Qunyan Yu,Lance Ostrom,Paul Fordjour,Dustin L. Anderson,John E. Monahan,Joseph F. Kelleher,Stefan Peukert,Shifeng Pan,Xu Wu,Sauveur-Michel Maira
标识
DOI:10.1126/scitranslmed.3001599
摘要
Resistance of medulloblastoma to Smo antagonists can be delayed or prevented by specific drug combinations.
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