生物
大豆
染色质
基因
遗传学
基因表达
基因表达调控
基因复制
基因组
驯化
甘氨酸
氨基酸
作者
Longfei Wang,Guanghong Jia,Xinyu Jiang,Weidong Song,Zhenyu Chen,Qingxin Song
出处
期刊:The Plant Cell
[Oxford University Press]
日期:2021-03-17
卷期号:33 (5): 1430-1446
被引量:31
标识
DOI:10.1093/plcell/koab081
摘要
Polyploidy or whole-genome duplication (WGD) is widespread in plants and is a key driver of evolution and speciation, accompanied by rapid and dynamic changes in genomic structure and gene expression. The 3D structure of the genome is intricately linked to gene expression, but its role in transcription regulation following polyploidy and domestication remains unclear. Here, we generated high-resolution (∼2 kb) Hi-C maps for cultivated soybean (Glycine max), wild soybean (Glycine soja), and common bean (Phaseolus vulgaris). We found polyploidization in soybean may induce architecture changes of topologically associating domains and subsequent diploidization led to chromatin topology alteration around chromosome-rearrangement sites. Compared with single-copy and small-scale duplicated genes, WGD genes displayed more long-range chromosomal interactions and were coupled with higher levels of gene expression and chromatin accessibilities but void of DNA methylation. Interestingly, chromatin loop reorganization was involved in expression divergence of the genes during soybean domestication. Genes with chromatin loops were under stronger artificial selection than genes without loops. These findings provide insights into the roles of dynamic chromatin structures on gene expression during polyploidization, diploidization, and domestication of soybean.
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