Construction of bifunctionalized Co-V mixed metal oxide nanosheets with Co3+-Rich surfaces and oxygen defect derived from LDHs as nanozyme for antibacterial application

With the rapid development of multiple functional nanozymes, the research on the unique characteristic, contributing to the enzyme-like activity, is essential for us to construct mimic enzymes with outstanding activity. Herein, 2D Co-V mixed metal oxides (MMOs) are prepared through Co-V layered double hydroxide (LDH) precursor. The single phase of Co-V LDHs is prepared by controlling the dosage of hexamethylenetetramine accurately in the coprecipitation system. After calcinated at 400 °C, the obtained Co-V MMOs, composed of Co3V2O8 and Co3O4, still inherite the microtopography of nanosheets from the precursor, which have superior surface properties to enhance the peroxidase/oxidase (POD/OXD)-like activity. 2D Co-V MMO nanosheets have excellent bactericidal properties in the presence of H2O2 as low as 1 μM. The enhanced catalytic performances are attributed to unique hybrid nanosheets architecture and synergistic effect of two active components, ranking the hybrid nanostructure as a promising antibacterial material.