Preparation and Properties of Calcium Doped Carbon Nanofibers Photothermal Reagent

Recently, carbon nanomaterials illustrated great application prospect in tumor photothermal therapy (PTT). Meanwhile, numerous studies have shown that destruction of calcium homeostasis in cells can also be used as an effective strategy to inhibit tumor. Therefore, dual effect Ca 2+ doped carbon nanofibers (PCNFs-Ca) photothermal reagents were prepared by electrospinning technique in this study. The spinnability, morphology and photothermal effect of different content of calcium doped carbon nanofibers were analyzed by field emission scanning electron microscopy (SEM), X-ray diffraction (XRD) and infrared thermometer. The results suggested that a dual effect photothermal reagent with high Ca 2+ content was prepared to achieve significant effect in tumor inhibition on the premise of less influence on the photothermal properties of carbon nanofibers.