扁平部
玻璃体切除术
医学
眼内炎
眼科
荟萃分析
抗菌剂
相对风险
外科
视力
置信区间
内科学
有机化学
化学
作者
Parsa Mehraban Far,Shanna C. Yeung,Pedram Laghaei Farimani,Jenny Qian,Angela Q. Zhang,Peter J. Kertes,Yuyi You,Peng Yan
出处
期刊:Retina-the Journal of Retinal and Vitreous Diseases
[Ovid Technologies (Wolters Kluwer)]
日期:2021-10-01
卷期号:41 (10): 2009-2016
被引量:10
标识
DOI:10.1097/iae.0000000000003203
摘要
To compare the visual outcomes after prompt pars plana vitrectomy (PPV) with tap biopsy and intravitreal antimicrobial injection to treat postinjection and postsurgery endophthalmitis.The Cochrane Central Register of Controlled Trials, Ovid MEDLINE, and Ovid Embase databases were searched for articles published between January 2010 and November 2020. Two independent reviewers selected articles and extracted data. We analyzed data in RevMan 5.3 and assessed methodological quality using the Cochrane ROBINS-I tool. The mean improvement in visual outcome was compared between PPV and intravitreal antimicrobial injection as a relative risk of improving ≥2 lines and a mean logarithm of the minimal angle of resolution difference in improvement.Fifteen retrospective case series (1,355 eyes), of which 739 eyes (55%) received intravitreal antimicrobial injection and 616 (45%) received PPV as initial treatment, were included. The overall relative risk of improving 2 or more lines in PPV in comparison with intravitreal antimicrobial injection was 1.04 (95% CI 0.88-1.23; P = 0.61; I2 = 0%) with a mean difference of 0.04 (95% CI -0.18 to 0.27; P = 0.69; I2 = 0%). The results stayed robust when subgroup analysis based on causative procedure for endophthalmitis was performed.Intravitreal antimicrobial injection is noninferior to PPV for the treatment of postcataract operation, postinjection, and post-PPV endophthalmitis.
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