Mild and moderate cognitive impairments: clinical manifestations, etiology, pathogenesis, treatment approaches

The paper discusses the prevalence, clinical manifestations, and possibilities of treatment of moderate cognitive impairments (MCI). Criteria for the diagnosis of MCI are considered in detail. The evolution of views on MCI and the current ideas on this syndrome are described. Neuropsychologicalfeatures in MCI are detailed in relation to their etiology. The main lines of MCI treatment and the data of an interregional study of the efficacy of akatinol memantine in patients with MCI of varying etiology are given.