Efficacy of Compound Dracorhodin vs.Sulfasalazine Coloclysis for Ulcerative Colitis

OBJECTIVE: To evaluate the curative efficacy and side effects of Compound-dracorhodin vs.Sulfasalazine(SASP) coloclysis for active ulcerative colitis.METHODS: By randomized double blind method,the curative efficacy and side effects of Compound-dracorhodin vs.Sulfasalazine(SASP) coloclysis for active ulcerative colitis in 85 cases were observed,with a course of treatment of 20 days.RESULTS: After 20-day treatment,significant differences were noted between the two groups in clinical,endoscopic and histological responsive rates(68.8%,70.8% and 77.1%,respectively in Compound-dracorhodin treatment group vs.45.9%,48.6% and 54.1%,respectively in Sulfasalazine group,P0.05).CONCLUSION: Compound-dracorhodin coloclysis is superior to Sulfasalazine(SASP) coloclysis in that it has good efficacy yet with mild side-effects for patients with active ulcerative colitis.