Synthesis, characterization, & biological activity of some amino-acids & mixed amino-acid complexes of Fe (III) ions

Amino acid complexes [M(L)2]Cl, [M(L)(L)]Cl, and [M(L)(L)(L)] type of Fe (III) ion with (Gly), and mixed amino acid ligands (Arg+Asp), and (Arg +Asp+Ser), respectively, have been synthesized and characterized using EDX, FTIR, UV/Vis, TGA, XRD, spectra and conductivity measurements. All amino acid ligands with Fe (III) ion have been found to act as bidentate chelating agents coordinating through COO -and NH2. The antibacterial activity of amino acid complexes was evaluated against four bacteria strains, two kind of grampositive (Staphylo coccus aureas, Klebsiella pneumonia), and two kind of gram negative (Escherichia coli, Pseudomonas aeruginosa). The Fe (III) complexes were found to have varied degree of inhibitory effect against bacteria.