血管舒张
药理学
医学
肺动脉高压
硝苯地平
肺动脉
伊马替尼
内科学
钙
髓系白血病
作者
Daniel Morales‐Cano,Bianca Barreira,María Callejo,Miguel A. Olivencia,Antonio Ferruelo,Javier Milara,José A. Lorente,Laura Moreno,Ángel Cogolludo,Francisco Pérez‐Vizcaíno
标识
DOI:10.1016/j.vph.2024.107371
摘要
An effective pulmonary hypertension (PH) treatment should combine antiproliferative and vasodilator effects. We characterized a wide-range of drugs comparing their anti-proliferative vs vasodilator effects in human and rat pulmonary artery smooth muscle cells (PASMC). Key findings: 1) Approved PH drugs (PDE5 inhibitors, sGC stimulators and PGI
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