癌症免疫疗法
肽
免疫疗法
化学
癌症研究
免疫系统
癌细胞
CD8型
噬菌体展示
细胞毒性T细胞
T细胞
生物化学
分子生物学
癌症
生物
免疫学
体外
遗传学
作者
Xiaoshuang Niu,Menghan Wu,Guodong Li,Xiuman Zhou,Wenpeng Cao,Wenjie Zhai,Aijun Wu,Xiaowen Zhou,Shengzhe Jin,Guanyu Chen,Yanying Li,Jiangfeng Du,Yahong Wu,Lu Qiu,Wenshan Zhao,Yanfeng Gao
标识
DOI：10.1016/j.apsb.2023.08.003
摘要
Developing new therapeutic agents for cancer immunotherapy is highly demanding due to the low response ratio of PD-1/PD-L1 blockade in cancer patients. Here, we discovered that the novel immune checkpoint VISTA is highly expressed on a variety of tumor-infiltrating immune cells, especially myeloid derived suppressor cells (MDSCs) and CD8
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