头皮
医学
皮肤病科
观察研究
多汗症
肉毒毒素
梅德林
外科
内科学
政治学
法学
作者
Betty Nguyen,Sofia M. Perez,Antonella Tosti
出处
期刊:Dermatologic Surgery
[Ovid Technologies (Wolters Kluwer)]
日期:2023-08-08
卷期号:49 (11): 1023-1026
标识
DOI:10.1097/dss.0000000000003895
摘要
BACKGROUND Many reports have described the use of botulinum toxin (BTX) in the treatment of scalp conditions, but no studies have synthesized these collective findings. OBJECTIVE We conducted a systematic review to summarize the scalp conditions for which treatment with BTX has been described. METHODS We searched PubMed/MEDLINE and Scopus for articles in English published before November 1, 2022, using the keywords “hair” or “scalp” and BTX-related search terms. Articles that described patients who received injections of BTX for the management of scalp conditions were included. RESULTS Twenty-four original articles (12 case reports, 9 clinical trials, and 3 case series) were identified that described 309 patients with a scalp condition treated with BTX. Androgenetic alopecia, craniofacial hyperhidrosis, and scalp hyperseborrhea had the most robust data supporting the clinical efficacy of BTX. CONCLUSION The current quality of evidence is highly variable and, for many conditions, limited to small observational studies. Botulinum toxin may be a promising therapeutic option for patients with various scalp conditions, but future studies are needed to better understand its efficacy and safety.
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