桔霉素
马兜铃酸
真菌毒素
赭曲霉毒素A
肾毒性
化学
赭曲霉毒素
致癌物
伏马菌素B1
毒理
赭曲霉毒素
生物
毒性
生物化学
食品科学
有机化学
遗传学
作者
Kathleen G. Dickman,Arthur P. Grollman
出处
期刊:Elsevier eBooks
[Elsevier]
日期:2010-01-01
卷期号:: 433-458
被引量:5
标识
DOI:10.1016/b978-0-08-046884-6.00823-x
摘要
This chapter reviews the chemistry, toxicokinetics, and biological activities of natural nephrotoxins found in certain herbs used for medicinal purposes and in fungi associated with various foodstuffs. Aristolochic acid, a human carcinogen, is notable for its selective toxicity to the proximal tubule. Ochratoxin, fumonisin B1, and citrinin are mycotoxins produced by molds that infest agricultural products, while orellanine is a proximal tubule nephrotoxin found in certain species of mushroom.
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