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1658 积分 2024-07-23 加入
Abstract 3425: The discovery and characterization of CFT1946: A potent, selective, and orally bioavailable degrader of mutant BRAF for the treatment of BRAF-driven cancers
3天前
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The discovery and characterization of CFT1946: A potent, selective, and orally bioavailable degrader of mutant BRAF for the treatment of BRAF-driven cancers
4天前
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Structural and Physicochemical Features of Oral PROTACs
9天前
已完结
Transition-Metal (Cu, Pd, Ni)-Catalyzed Difluoroalkylation via Cross-Coupling with Difluoroalkyl Halides
18天前
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Unlocking Difluorocarbene as a Fluorocarbanion and a Fluorocarbon Radical Precursor for Sequential Catalytic Coupling
18天前
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Targeting cancer with small-molecule pan-KRAS degraders
27天前
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Lessons learned in linking PROTACs from discovery to the clinic
28天前
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The evolving landscape of drug targets
1个月前
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TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
1个月前
已完结