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874 积分 2021-07-15 加入
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
9天前
已完结
Novel drug targets in 2024
14天前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
26天前
已完结
Discovery of a Highly Potent and Selective Tyrosine Kinase 2 (TYK2) Degrader with In Vivo Therapeutic Efficacy in a Murine Psoriasis Model
1个月前
已完结
Study of the N7 Regioselective Glycosylation of 6-Chloropurine and 2,6-Dichloropurine with Tin and Titanium Tetrachloride
1个月前
已完结
Combination therapy and dual-target inhibitors based on cyclin-dependent kinases (CDKs): Emerging strategies for cancer therapy
1个月前
已完结
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit to Lead
1个月前
已完结
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors
1个月前
已完结
Efficient Synthesis of a Key Intermediate for Moxifloxacin Via Intramolecular Double Stereodifferentiation
2个月前
已完结
Diverse pharmacological activities of β-carbolines: Substitution patterns, SARs and mechanisms of action
2个月前
已完结
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