Lv61
1924 积分 2021-07-15 加入
Designing around Structural Alerts in Drug Discovery
1小时前
待确认
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
1个月前
已完结
Oral GLP-1 receptor agonist promotes astrocyte-neuron lactate and lipid transfer with neuroprotective effects
1个月前
已完结
Discovery of a Potent, Selective and In Vivo Active Aurora A PROTAC Degrader from a Promiscuous Kinase Inhibitor
2个月前
已完结
Discovery and Development of CH3127, a Prodrug of Semaglutide for Once Weekly Oral Tablet Dosing
2个月前
已关闭
Medicinal chemistry strategies to breach the blood–brain barrier: structural design principles for brain-targeted therapeutics
3个月前
已完结
Nickel-Catalyzed Intramolecular Dual Annulation Reaction of Alkyl Nitrile-Containing 1,2,3-Benzotriazin-4(3H)-ones: A Pathway to Access Diversely Polycyclic Quinazolinone Alkaloids
3个月前
已完结
Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment
3个月前
已完结
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, and Dose-Increasing Study on the Safety, Tolerability and PK/PD of Multiple Doses of HSK7653 by Oral Administration in Patients with Type 2 Diabetes Mellitus in China
4个月前
已完结
Design, Synthesis, and Evaluation of a Series of Novel Super Long-Acting DPP-4 Inhibitors for the Treatment of Type 2 Diabetes
4个月前
已完结