| 标题 |
 Association of low-carbohydrate diet score and carbohydrate quality index with colorectal cancer risk: a large-scale case-control study 低碳水化合物饮食评分和碳水化合物质量指数与结直肠癌风险的关系：一项大规模病例对照研究
相关领域
医学
优势比
置信区间
逻辑回归
结直肠癌
人口
病例对照研究
内科学
环境卫生
人口学
癌症
社会学
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| 网址 | |
| DOI | |
| 其它 |
Abstract Purpose Carbohydrate intake has been linked to colorectal cancer (CRC) risk, with variations depending on the quantity and quality of carbohydrates consumed. This study aimed to investigate the association between carbohydrate quantity and quality, using the low-carbohydrate diet score (LCD) and carbohydrate quality index (CQI), and the risk of CRC in the Chinese population. Methods We conducted a case–control study in Guangzhou, China, with 2,799 CRC cases and an equal number of sex- and age-matched controls. Dietary data were collected using a validated food frequency questionnaire to derive the LCD and CQI, assessing the quantity and quality of carbohydrate intake separately. Odds ratios (OR) and 95% confidence interval (CI) for CRC risk were estimated using unconditional logistic regression models, and restricted cubic splines were used to explore potential non-linear relationships. |
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