| 标题 |
  Mechanomedicine 相关领域
机械生物学
机械敏感通道
细胞生物学
生物
神经科学
离子通道
生物化学
受体
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| 网址 | |
| DOI |
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10.1007/s12551-018-0459-7
Doi
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| 其它 | 摘要：Mechanical forces act throughout the body across multiple scales, from organs and tissues to cells and molecules, playing a vital role in maintaining tissue integrity, regulating cellular functions and supporting physiological performance. Importantly, alterations in mechanical forces and properties can be hallmarks of tissue injury and disease, and can thus serve as valuable biomarkers for disease monitoring and diagnostics and can be harnessed to modulate biological processes for therapeutic benefit. This concept, termed mechanomedicine, offers an important strategy in disease diagnosis and therapy. In this Review, we first introduce biomechanics and mechanobiology as the underlying principles of mechanomedicine and outline the properties and measurements of key mechanical signatures in health and disease. |
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(2025-6-4)
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