| 标题 |
[高分] Comparative study to evaluate the effectiveness of atenolol and propranolol in the treatment of infantile haemangiomas
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| DOI |
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| 其它 |
Ashraf, R., Mahajan, R., Handa, S., Abas, M., De, D., Sinha, A. & Sachdeva, N. British Journal of Dermatology 2019 Pages 16 Abstract: Beta blockers, particularly propranolol, are the current drugs of choice in the management of infantile haemangiomas (IHs). In view of the relative lack of long-term safety data on propranolol, a nonselective lipophilic beta blocker, in infants, we set out to compare its effectiveness and safety with those of atenolol, a beta-1-selective hydrophilic beta blocker, in the management of IHs. In this observer-blinded randomized controlled trial, consecutive patients with complicated or cosmetically significant IHs and no contraindications to beta blockers were recruited over 1 year, after obtaining an informed written consent from parents. |
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(2025-6-4)