| 标题 |
[高分]
 Gasdermin E (GSDME)-mediated pyroptosis is activated in ICI-induced myocarditis: accumulation of cleaved GSDME fragments in cardiomyocytes not only precipitates membrane rupture but also drives release of proinflammatory cytokines, fueling local inflammation Gasdermin E(GSDME)介导的上睑下垂在ICI诱导的心肌炎中被激活：切割的GSDME片段在心肌细胞中的积累不仅导致膜破裂，而且驱动促炎细胞因子的释放，加剧局部炎症
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