| 标题 |
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Enhanced Mucoadhesion of Thiolated β‑Cyclodextrin by S‑Protection with 2‑Mercaptoethanesulfonic Acid |
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| 其它 |
This study aimed at designing an S-protected thiolated β-cyclodextrin (β- CD) exhibiting enhanced mucoadhesive properties. The native β-CD was thiolated with phosphorus pentasulfide resulting in a thiolated β-CD (β-CD-SH) and subsequently S- protected with 2-mercaptoethanesulfonate (MESNA) to form β-CD-SS-MESNA. The structure of the novel excipient was confirmed by 1H NMR and Fourier-transform infrared spectroscopy. |
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(2025-6-4)