| 标题 |
Immune trafficking perturbation between lymph nodes and tumors triggers T-cell dysregulation and targetable B-cell programs in pMMR colorectal cancer
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描述信息：The response to immunotherapy in mismatch repair proficient (pMMR) and deficient (dMMR) colorectal cancer (CRC) varies greatly, but the immunological basis in particular the roles of tumor-draining lymph nodes (TDLNs) remains unclear.We create cross-tissue immune atlas to depict the cellular and spatial basis of TDLNs as potential mechanisms of immune evasion and enlightens treatment development for overcoming pMMR immune resistance. 疾病名称:colorectal cancer BioProject编号:PRJCA055466 |
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(2025-6-4)
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