PORCINE COLLAGEN: EVOLENCE

Evolence and Evolence Breeze (ColBar LifeScience Ltd.) are the latest products available in the evolution of collagen-derived fillers. Both Evolence and Evolence Breeze are produced from the same porcine collagen and are formulated at collagen concentrations of 35 mg/mL. The products differ in their rheologic properties, which are reflected in their viscosity and injectability properties. The viscosity of Evolence Breeze is approximately 60% of the viscosity of Evolence and is injectable through a 30-gauge needle. The force that is needed to inject Evolence Breeze from the syringe (extrusion force) through a 30-gauge needle at a flow rate of 1 mL/min is 10 N. Evolence exhibits a similar extrusion force as Evolence Breeze of about 10 N when tested on a 27-gauge needle.