脂类学
鞘脂
计算生物学
新陈代谢
生物
生物化学
作者
Aleksandra Gruevska,Jack Leslie,Elena Perpiñán,Hannah Maude,Amy Collins,Scott E. Johnson,Laura Evangelista,Eleanor Sabey,Jeremy French,Steven White,John Moir,Stuart Robinson,Wasfi Alrawashdeh,Rohan Thakkar,Roberta Forlano,Pinelopi Manousou,Robert Goldin,David Carling,Matthew Hoare,Mark Thursz
标识
DOI:10.1016/j.metabol.2025.156237
摘要
Our spatial multi-omics approach suggests cell type-specific mechanisms of fibrogenesis involving sphingolipid metabolism. Importantly, sphingolipid metabolic pathways are modifiable targets, which may have potential as an anti-fibrotic therapeutic strategy.
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