医学
膀胱癌
膀胱镜检查
泌尿系统
DNA甲基化
尿
细胞学
甲基化
癌症
膀胱
泌尿科
内科学
肿瘤科
病理
DNA
生物
遗传学
基因表达
基因
作者
In Gab Jeong,Sung‐Cheol Yun,Hong Koo Ha,Sung Gu Kang,Sangchul Lee,Sungchan Park,Hyun Hwan Sung,Sun Il Kim,Eu Chang Hwang,Kyung Cheol Moon,Cheol Kwak
出处
期刊:JAMA Oncology
[American Medical Association]
日期:2025-01-30
卷期号:11 (3): 293-293
被引量:16
标识
DOI:10.1001/jamaoncol.2024.6160
摘要
In this prospective multicenter study of individuals with hematuria, the urinary DNA methylation test showed 89% sensitivity for detecting high-grade or invasive bladder cancer, outperforming the NMP22 test or urine cytology test with high specificity. While this test had an excellent negative predictive value, its positive predictive value was suboptimal.
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