Feasibility of modified double-layered suturing for a large mucosal defect after duodenal endoscopic submucosal dissection (Origami method)

Modified double-layered suturing (Origami method; OGM), which can achieve robust closure even for large mucosal defects by folding the muscle layer using only through-the-scope clips. This study aimed to evaluate the feasibility of this OGM in duodenal ESD.