纳米技术
抗坏血酸
生物传感器
材料科学
基质(水族馆)
生物分子
金属有机骨架
微流控
原位
灵活性(工程)
化学
有机化学
吸附
海洋学
食品科学
统计
数学
地质学
作者
Zihe Li,Zihe Li,Long Tang,Xin Yi,Jiaxin Zhou,Xue Jiang,Xiandeng Hou
标识
DOI:10.1016/j.trac.2024.117709
摘要
Throughout the past ten years, metal-organic frameworks (MOFs) represent a class of coordination polymers characterized by high porosity and structural flexibility, and are increasingly used in biochemical analysis. However, largely due to the extremely-low content of biomolecules, the transferability and support between MOFs material and sensing substrate are crucial for sensing sensitivity and stability, which directly affect their practical applications. Rapid in-situ MOF synthesis strategy is obviously very important, which usually involves the direct growth of MOFs onto the sensing substrate in a "one-pot" process for simple, fast, portable and ideally large-scale preparation. This review focuses on the most current developments in the field of using MOFs produced quickly in-situ for highly sensitive detection of tiny amounts of protein, glucose, dopamine, ascorbic acid and uric acid by electrochemical, fluorescence, Raman, colorimetric sensing and microfluidics techniques.
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