纳米技术
药物输送
纳米材料
纳米颗粒
生物相容性
靶向给药
药品
化学
材料科学
药理学
医学
有机化学
作者
Xiaoxuan Yu,Zihui Weng,Ziyang Zhao,Jing Xu,Zhenhui Qi,Junqiu Liu
出处
期刊:Pharmaceutics
[MDPI AG]
日期:2022-11-26
卷期号:14 (12): 2609-2609
被引量:7
标识
DOI:10.3390/pharmaceutics14122609
摘要
Nanoparticles (NPs) have been widely used as target delivery vehicles for therapeutic goods; however, compared with inorganic and organic nanomaterials, protein nanomaterials have better biocompatibility and can self-assemble into highly ordered cage-like structures, which are more favorable for applications in targeted drug delivery. In this review, we concentrate on the typical protein cage nanoparticles drugs encapsulation processes, such as drug fusion expression, diffusion, electrostatic contact, covalent binding, and protein cage disassembly/recombination. The usage of protein cage nanoparticles in biomedicine is also briefly discussed. These materials can be utilized to transport small molecules, peptides, siRNA, and other medications for anti-tumor, contrast, etc.
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