化学
废止
吡咯
催化作用
生物碱
尿素
烯烃
组合化学
药物化学
立体化学
有机化学
作者
Grace E. Hubbell,Jetze J. Tepe
出处
期刊:Organic Letters
[American Chemical Society]
日期:2022-09-09
卷期号:24 (37): 6740-6744
被引量:1
标识
DOI:10.1021/acs.orglett.2c02508
摘要
A Rh(III)-catalyzed C-H activation/annulation with an imidazolone as alkene partner is reported to access dihydroisoquinolone-fused imidazolin-2-ones. These bicycles are reminiscent of scaffolds belonging to the pyrrole alkaloid family of natural products. This approach facilitates construction of a variety of urea-fused dihydroisoquinolone scaffolds including heterocyclic moieties.
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